Subjects: Optics >> Quantum optics submitted time 2023-02-19
C. Gong
X. Yang
S. J. Tang
Q. Q. Zhang
Y. Wang
Y. L. Liu
Y. C. Chen
G. D. Peng
X. Fan
Y. F. Xiao
Y. J. Rao
Y. Gong
Abstract： Biomarker detection is the key to identifying health risks. However, designing sensitive biosensors in a single-use mode for disease diagnosis remains a major challenge. Here, we report sub-monolayer biolasers with remarkable repeatability for ultrasensitive and disposable biomarker detection. The biolaser sensors are designed by employing the telecom optical fibers as distributed optical microcavities and pushing the gain molecules down to the sub-monolayer level. We observe a status transition from the monolayer biolaser to the sub-monolayer biolaser by tuning the specific conjugation. By reducing the fluorophores down to the threshold density (~ 3.2 x 10-13 mol/cm2), we demonstrate an ultimate sensitivity of sub-monolayer biolaser with six orders of magnitude enhancement compared with the monolayer biolasers. We further achieved ultrasensitive immunoassay for Parkinson's disease biomarker, alpha-synuclein, with a lower limit of detection of 0.32 pM in serum. This biosensor with massive fabrication capability at ultralow cost provides a general method for the ultrasensitive disposable biodetection of disease biomarkers.
Peer Review Status:
Awaiting Review
Subjects: Optics >> Quantum optics submitted time 2023-02-19
H. -X. Yang
J. -Y. Ma
Y. -K. Wu
Y. Wang
M. -M. Cao
W. -X. Guo
Y. -Y. Huang
L. Feng
Z. -C. Zhou
L. -M. Duan
Abstract： Trapped ions constitute one of the most promising systems for implementing quantum computing and networking. For large-scale ion-trap-based quantum computers and networks, it is critical to have two types of qubits, one for computation and storage, while the other for auxiliary operations like runtime qubit detection, sympathetic cooling, and repetitive entanglement generation through photon links. Dual-type qubits have previously been realized in hybrid systems using two ion species, which, however, introduces significant experimental challenges for laser setup, gate operations as well as the control of the fraction and positioning of each qubit type within an ion crystal. Here we solve these problems by implementing two coherently-convertible qubit types using the same ion species. We encode the qubits into two pairs of clock states of the 171Yb+ ions, and achieve fast and high-fidelity conversion between the two types using narrow-band lasers. We further demonstrate that operations on one qubit type, including sympathetic laser cooling, gates and qubit detection, have crosstalk errors less than 0.03% on the other type, well below the error threshold for fault-tolerant quantum computing. Our work showcases the feasibility and advantages of using coherently convertible dual-type qubits with the same ion species for future large-scale quantum computing and networking.
Peer Review Status:Awaiting Review
Subjects: Optics >> Quantum optics submitted time 2023-02-19
Y. Li
N. An
Z. Lu
Y. Wang
B. Chang
T. Tan
X. Guo
X. Xu
J. He
H. Xia
Z. Wu
Y. Su
Y. Liu
Y. Rao
G. Soavi
B. Yao
Abstract： Surface plasmons in graphene provide a compelling strategy for advanced photonic technologies thanks to their tight confinement, fast response and tunability. Recent advances in the field of all optical generation of graphene plasmons in planar waveguides offer a promising method for high speed signal processing in nanoscale integrated optoelectronic devices. Here, we use two counter propagating frequency combs with temporally synchronized pulses to demonstrate deterministic all optical generation and electrical control of multiple plasmon polaritons, excited via difference frequency generation (DFG). Electrical tuning of a hybrid graphene fibre device offers a precise control over the DFG phase matching, leading to tunable responses of the graphene plasmons at different frequencies across a broadband (0 - 50 THz) and provides a powerful tool for high speed logic operations. Our results offer insights for plasmonics on hybrid photonic devices based on layered materials and pave the way to high speed integrated optoelectronic computing circuits.
Peer Review Status:Awaiting Review
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