摘要: In this paper, a universal wave equation of the motion of microscopic particles in curved space-time is established, which satisfies the conservation of probability. Under the classical limit conditions, the wave equation returns to the dynamic equation of special relativity. The application of the wave equation in the evolution of a flat expanding universe has preliminarily proved the correctness of the equation, and the new wave equation may open a window for us to understand physics within the Planck scale.